Priv.-Doz. Dr. med. Markus Hufnagel, DTM&H
Contact
Center for Pediatrics and
Adolescent Medicine, Clinic I
Division of Pediatric Infectious Diseases, Immunology and Vaccinology
University Hospital Freiburg
Mathildenstr. 1
D-79106 Freiburg
Germany
Tel: +49 (0)761-2704300
Email:
- Curriculum Vitae
- Professional Experience
- Education, Training & Degrees
- Grants & Professional Memberships
- Original Published Research
- Medical Reviews
- Medical Book Contributions
Curriculum Vitae
Professional Experience
2010 – Present |
Attending Physician ("Oberarzt"), Director of Pediatric Oupatient Clinic; |
Mar 2010 |
Visiting Lecturer and Infectious Diseases / Tropical Medicine Consultant |
2009 |
Acting Attending Physician ("Funktionsoberarzt"); |
Dec 2008 |
Visiting Lecturer and Infectious Diseases Consultant |
2007 – 2008 |
Senior Physician and Lecturer, Specialist in Pediatric Infectious Diseases, and Pediatric Rheumatology Fellow |
Apr – May 2007 |
Tropical Medicine Fellow |
2005 – 2007 |
Senior Physician, Pediatric Infectious Diseases Fellow, and |
2003 – 2005 |
Pediatric Resident and Assistant Director |
2000 – 2003 |
Research Fellow in Microbiology of Infectious Diseases |
1995 – 2000 |
Pediatric Resident and Assistant |
1994 |
Research Fellow in Immunology of Infectious Diseases |
1992 – 1994 |
Physician in Training ("Arzt im Praktikum") |
Education, Training & Degrees
| 2010 | Board Certification as Pediatric Rheumatologist |
| 2009 | Board Certification as Physician for Infectious Diseases |
| 2009 | Postdoctoral Medical Teaching Degree ("Habilitation") |
| 2009 | Good Clinical Practice (GCP) Training Certification |
| 2007 | Certification as Pediatric Infectious Disease Specialist |
2005 |
Board Certification as Physician for Pediatrics and Adolescent Medicine ("Facharzt") |
1995 |
Diploma Course and License in Tropical Medicine and Hygiene |
1994 |
Approval of Medical Doctoral Thesis ("Promotion") |
1994 |
Medical License ("Approbation als Arzt") |
1992 |
Medical Certification ("Medizinisches Staatsexamen") |
1984 – 1992 |
Medical School, Study of Human Medicine |
Grants
2010 |
German Academic Exchange Service (Deutscher Akademischer Austausch Dienst - DAAD) Travel Grant to participate as a Lecturer at the Tropical Medicine, Infectious Diseases and Molecular Biology Summer School |
2008 |
European Society for Paediatric Infectious Diseases (ESPID) |
2005 |
German Society for Pediatric Infectious Diseases (DGPI) |
1999 |
"Walter-Marget Vereinigung zur Förderung der Infektiologie" |
Professional Memberships
- German Society of Pediatrics and Adolescent Medicine (DGKJ)
- German Society for Pediatric Infectious Diseases (DGPI)
- German Society of Pediatric Rheumatology (GKJR)
- German Working Group for Tropical Pediatrics (ATP)
- European Society for Paediatric Infectious Diseases (ESPID)
Original Published Research
Schenk T, Maier B, Hufnagel M, Strahm B, Kontny U, Neumann-Haefelin D, Falcone V (2010)
Persistence of HBoV in immunocompromised patients.
Pediatr Infect Dis J, (currently on press)
Carlsson G, Hufnagel M, Jansen O, Claviez A, Nabavi A (2010)
Rapid recovery of motor and cognitive functions after resection
of a right frontal lobe meningioma in a child.
Childs Nerv Syst. 26:105-111
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Hatz C, Werlein J, Mutsch M, Hufnagel M, Behrens RH (2009)
Japanese Encephalitis: Defining Risk Incidence for Travelers to Endemic Countries and Vaccine Prescribing From the UK and Switzerland.
J Travel Med, 16:200-203
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von Schnakenburg C, Hufnagel M, Superti-Furga A, Rieger-Fackeldey E, Berner R (2009)
Successful Continuous Renal Replacement Therapy in a Neonate with Early-onset Group B Streptococcal Sepsis and Multi-organ Dysfunction Syndrome.
[Multiorganversagen bei Early-onset-B-Streptokokkensepsis: Erfolgreicher Einsatz einer kontinuierlichen venovenösen Hämofiltration (CVVH) beim Neugeborenen.]
Klin Padiatr. 221:251-3. German.
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Hufnagel M, Burger A, Bartelt S, Henneke P, Berner R (2008)
Secular trends in pediatric bloodstream infections over a 20-year period at a tertiary care hospital in Germany.
European Journal of Pediatrics, 167:1149-59
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Hufnagel M, Liese C, Löscher C, Kunze K, Prömpeler H, Berner R, Krüger M (2007)
Enterococcal colonization of infants in a neonatal intensive care unit: Seasonal patterns and associated risk factors.
BMC Infectious Diseases, 7:107
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Schenk T, Strahm B, Kontny U, Hufnagel M, Neumann-Haefelin D, Falcone V (2007)
Disseminated human bocavirus infection in a child following hematopoietic stem cell transplantation.
Emerging Infectious Diseases, 13:1425-1427
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Hufnagel M, Carey VJ, Baldassarri L, Reinert RR, Huebner J (2006)
Distribution of four capsular serotypes of Enterococcus faecalis among clinical isolates from different geographical origins and infection sites.
Infection, 34:22-25
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Buck D, Malivert L, de Chasseval R, Barraud A, Fondanèche M-C, Sanal O, Plebani A, Stèphan J-L, Hufnagel M, le Deist F, Fischer A, Durandy A, de Villartay JP, Revy P (2006)
Cernunnos, a novel nonhomologous end-joining factor, is mutated in human immunodeficiency with microcephaly.
Cell, 124:287-299
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Hufnagel M, Czech N, Schmidt M, Hero B, Claviez A (2006)
Neuroblastoma Stage 4S with 123I-MIBG-positive bone marrow involvement.
Pediatric Blood & Cancer, 46:264-265
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Hufnagel M, Huebner J (2005)
Analysis of the specific immune response against capsular polysaccharides of two patients with systemic enterococcal infections.
Infection, 33:373-376
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Kropec A, Hufnagel M, Zimmermann K, Huebner J (2005)
In vitro assessment of the host response against Enterococcus faecalis in probiotic preparations.
Infection, 33:377-379
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Hufnagel M, Kropec A, Theilacker C, Huebner J (2005)
Naturally acquired antibodies against four Enterococcus faecalis capsular polysaccharides in normal human sera.
Clinical and Vaccine Immunology (formerly Clinical and Diagnostic Laboratory Immunology), 12:930-934
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Hufnagel M, Hancock LE, Koch S, Theilacker C, Gilmore MS, Huebner J (2004)
Serological and genetic diversity of capsular polysaccharides in Enterococcus faecalis.
Journal of Clinical Microbiology, 42:2548-2557
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Hufnagel M, Koch S, Creti R, Baldassarri L, Huebner J (2004)
A putative sugar-binding transcriptional regulator in a novel gene locus in Enterococcus faecalis contributes to biofilm formation and prolonged bacteremia in mice.
Journal of Infectious Diseases, 189:420-430
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Hufnagel M, Koch S, Kropec A, Huebner J (2003)
Opsonophagocytic assay as a potentially useful tool for assessing safety of Enterococcal preparation.
International Journal of Food Microbiology, 88:263-267
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Lässker U, Harder TC, Hufnagel M, Suttorp M (2002)
Rapid molecular discrimination of infection with wild-type varicella zoster virus or varicella vaccine virus.
Infection, 30:320-322
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Harder TC, Hufnagel M, Zahn K, Beutel K, Schmitt HJ, Ullmann U, Rautenberg P (2001)
A new LightCyclerTM polymerase chain reaction for rapid and sensitive quantification of parvovirus B19 DNA guides therapeutic decision-making in chronic infections.
Journal of Clinical Microbiology, 39:4413-4419
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Eichmann D, Hufnagel M, Quick P, Santer R (1999)
Treatment of hyperinsulinemic hypoglycemia with nifedipine.
European Journal of Pediatrics, 158:204-206
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Muller D, Hufnagel M, Suttorp (1999)
Accidental overdose of vancomycin in preterm twins.
Pediatric Infectious Diseases Journal, 18:744-745
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Hufnagel M, Eichmann D, Stieh J, Santer R (1998)
Further evidence for a dominant form of familial persistent hyperinsulinemic hypoglycemia of infancy: a family with documented hyperinsulinemia in two generations.
Journal of Clinical Endocrinology and Metabolism, 83:2215-2216
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Dai WJ, Bartens W, Kohler G, Hufnagel M, Kopf M, Brombacher F (1997)
Impaired macrophage listericidal and cytokine activities are responsible for the rapid death of Listeria monocytogenes-infected IFN-gamma receptor-deficient mice.
Journal of Immunology, 158:5297-5304
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Hufnagel M, Niemeyer C, Zimmerhackl LB, Tuchelmann T, Sauter S, Brandis M (1995)
Hemophagocytosis: a complication of acute Q fever in a child.
Clinical Infectious Diseases, 21:1029-1031
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Hufnagel M, Tuchelmann, Zimmerhackl LB, Leititis JU, Tüchelmann T, Brandis M,
Brem S, Schindera F (1994)
Acute renal failure without liver involvement in Leptospirosis icterohaemorrhagiae infection. [Akutes Nierenversagen ohne Leberbeteiligung bei Leptospira icterohaemorrhagiae-Infektion.]
Monatsschr Kinderheilkd 142:957-960. German.
Medical Reviews
Kenzel S, Hufnagel M, Berner R, Henneke P (2010)
Pneumococcus Vaccination and Serotype Replacement: Do we need a new vaccine or vaccination concept? [Pneumokokkenimpfung und Serotyp-Replacement: Brauchen wir ein neues Impf(stoff)konzept?.]
Dtsch Med Wschr, 135:1198-1200. German.
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Lander F, Hufnagel M, Berner R (2010)
Antimicrobial therapy for sepsis in pediatrics.
[Antimikrobielle Therapie der Sepsis in der Pädiatrie.]
Pädiat Prax. 75:233-245. German.
Weih M, Schaller G, Degirmenci U, Hufnagel M, Kornhuber J (2009)
Differential diagnosis of neurodegenerative disorders in young adults.
[Differentialdiagnosen zu neurodegenerativen Erkrankungen im jungen Erwachsenenalter.]
Fortsch Neurol Psychiatr, 77(11):662-668. German.
Hufnagel M, Berner R (2009)
Lymphadenitis colli – a guideline for diagnostic and therapeutic procedures.
[Lymphadenitis colli – ein Leitfaden für das diagnostische und therapeutische Vorgehen.]
Kinder- und Jugendarzt, 40:300-11. German.
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Hufnagel M, Henneke P, Krüger M, Berner R (2008)
Severe, rapid-onset sepsis in childhood. [Die foudroyante Sepsis im Kindesalter.]
Up2date Notfallmedizin, 3:149-171. German.
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Hufnagel M, Burger A, Zwigart M, Berner R (2008)
Epidemiology of Staphylococcus aureus bacteremia in childhood – "secular trends."
[Epidemiologie von Staphylococcus aureus-Bakteriämien im Kindesalter – "säkulare Trends."]
Kinder- und Jugendmedizin, 8:88-92. German.
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Hufnagel M, Berner R (2007)
Lice, fleas and other beasts. [Läuse, Flöhe und anderes Getier.]
Kinderkrankenschwester, 26:283-8. German.
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Hufnagel M, Neef V, Berner R (2007)
White tongue in Infants – not always oral thrush.
[Die weiße Zunge beim Säugling – nicht immer ein Mundsoor.]
Kinderärztliche Praxis 78:152-154. German.
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Koch S, Hufnagel M, Huebner J (2004)
Treatment and prevention of enterococcal infections – alternative and experimental approaches.
Expert Opinion on Biological Therapy, 4:1519-31
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Koch S, Hufnagel M, Theilacker C, Huebner J (2004)
Enterococcal infections: host response, therapeutic, and prophylactic possibilities.
Vaccine, 22:822–830
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Hufnagel M (2001)
Hand, mouth, foot disease. [Hand-Mund-Fuß-Krankheit.]
Deutsche Medizinische Wochenschrift, 126:1125-1126. German.
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Hufnagel M, Schmitt HJ (1999)
Acute fever in travelers returning from the tropics. [Akutes Fieber bei Tropenrückkehrern.] Kinderärztliche Praxis 7:496-503. German.
Hufnagel M, Schmitt HJ (1999)
Chronic fever in travelers returning from the tropics.
[Chronisches Fieber bei Tropenrückkehrern.]
Kinderärztliche Praxis 7:504-509. German.
Medical Book Contributions
Hufnagel M (2009, 2003, 2000)
Legionella [Legionellose]
Chapter in "Handbuch Infektionen bei Kindern und Jugendlichen, [Handbook of Infectious Diseases in Children and Adolescents]," ed. Deutsche Gesellschaft für pädiatrische Infektiologie. Georg Thieme Verlag Stuttgart, pp. 332-5. German.
Hufnagel M (2009, 2003, 2000)
Leptospirosis [Leptospirose]
Chapter in "Handbuch Infektionen bei Kindern und Jugendlichen, [Handbook of Infectious Diseases in Children and Adolescents]," ed. Deutsche Gesellschaft für pädiatrische Infektiologie. Georg Thieme Verlag Stuttgart, pp. 344-6. German.
Hufnagel M (2008)
Pneumococcus: The Clinical Picture [Pneumokokken: Das Krankheitsbild]
Chapter in "Konjugatimpfstoffe und Infektionskrankheiten durch bekapselte Erreger." [Conjugate Vaccines and Infectious Diseases Caused by Capsulated Microorganisms],
ed. Berner R. Uni-Med Science, 1:25-35. German.
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Schmitt HJ, Hufnagel M (2007, 2003, 2001)
Typhus and Cholera Vaccination [Typhus- und Choleraschutzimpfung]
Chapter in "Pädiatrie Grundlagen und Praxis, [Pediatric Fundamentals and Practice]," eds. Lentze MJ, Schaub J, Schulte FJ, Spranger J. Springer-Verlag Berlin, pp. 95-96. German.
Hufnagel M, Schmitt HJ (2007, 2003, 2001)
Chlamydia Infections [Chlamydien-Infektionen]
Chapter in "Pädiatrie Grundlagen und Praxis, [Pediatric Fundamentals and Practice]," eds. Lentze MJ, Schaub J, Schulte FJ, Spranger J. Springer-Verlag Berlin, pp. 773-6. German.
Hufnagel M, Schmitt HJ (2007, 2003, 2001)
Q-Fever [Q-Fieber]
Chapter in "Pädiatrie Grundlagen und Praxis,[Pediatric Fundamentals and Practice]," eds. Lentze MJ, Schaub J, Schulte FJ, Spranger J. Springer-Verlag Berlin, pp. 798-9. German.
Hufnagel M, Schmitt HJ (2007, 2003, 2001)
Sepsis
Chapter in "Pädiatrie Grundlagen und Praxis, [Pediatric Fundamentals and Practice]," eds. Lentze MJ, Schaub J, Schulte FJ, Spranger J. Springer-Verlag Berlin, pp. 739-44. German.
Hufnagel M, Schmitt HJ (2007, 2003, 2001)
Toxic Shock Syndrome [Toxisches Schocksyndrom]
Chapter in "Pädiatrie Grundlagen und Praxis, [Pediatric Fundamentals and Practice]," eds. Lentze MJ, Schaub J, Schulte FJ, Spranger J. Springer-Verlag Berlin, pp. 744-6. German.